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Drug-mediated regulation of GPx1 expression In addition to iberin, which is discussed above, other chemical agents regulate GPx1 expression: docosahexaenoic acid [157] and Lfcin-B [158] suppress GPx1 expression, whereas other compounds, such as genistein [159] and resveratrol [160], upregulate GPx1 expression

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Chronic inflammation around hair follicles can damage stem cell populations residing in the bulge region, potentially explaining why some follicles eventually lose their ability to produce hair entirely